Writing fiction is not “self-­expression” or “therapy”. Novels are for readers, and writing them means the crafty, patient, selfless construction of effects. I think of my novels as being something like fairground rides: my job is to strap the reader into their car at the start of chapter one, then trundle and whizz them through scenes and surprises, on a carefully planned route, and at a finely engineered pace.

Many creative people, especially the young, may feel their chaotic or disordered relationship with the world is indispensable to their creative freedom. The more anarchic, the better! However, after considerable fieldwork in this area, I have yet to find it so. I have come to understand that the muscle of the imagination is strengthened through resistance, discipline and order.

But my own mottos are, “Don’t imagine for a moment that you’re going to be able to express yourself.” ... And most aspiring artists think, “I have something to say.”

Perfection is always a desired goal, but it cannot be a primary goal. Expression has to be the primary goal, because otherwise, there is no need for an actual person to be there.

In fact, what I usually say to people, “Probably some of the most successful scientists are the ones that know how to deal with failure well.” Because it’s easy to feel good when you succeed. That’s an easy thing. But you’re probably going to fail in science a lot more than you succeed, so you really have to learn how to deal with it and not let it beat you.

The person that inspired me the most was Judah Folkman. He was the man that I worked with when I was a postdoctoral fellow. He was really an inspirational person for a variety of reasons. One, he was a big thinker, and lots of people told him that his ideas wouldn’t work or that they were impossible. He persevered in spite of that, and did very, very well. And secondly, he was very encouraging, very sort of like positive reinforcement, in terms of how he would deal with me and others. So I would say he certainly had a pivotal influence on my career when I was a postdoctoral fellow.

A typical day is probably lots of meetings and stuff. But if it’s an idea that we’re developing, what might happen is I might talk to some of the people in the lab, maybe have them come in the office and brainstorm with them, and say, “Well, here’s a problem that we need to solve,” or need to solve better. So just as an example, when I had this idea that we could create better materials, I got about four or five people together with different backgrounds — chemistry, engineering, safety, toxicology — and we started putting chemical structures on the blackboard and say, “Well, this might work,” or “This might not be safe,” and ended up with certain structures that we thought would be good. And then, one of the guys would go out and try to make those structures, and we’d go from there.