My contemporaries were more upset about the Nobel than I was not to be recognised. One of them labelled it the 'No-Bell' prize! But it was fine by me. There's no Nobel Prize in astronomy and I was really proud that it was my stars that had convinced the prize committee that there was good physics in astrophysics.

We made one mistake in a story in which we said that — Woodward and Bernstein said — that there was a slush fund of $300,000 set up in the Committee to Re-elect the President, and it was controlled by Haldeman, and that one of the witnesses had testified to that slush fund to the grand jury investigating Watergate. ... It turned out that he hadn’t been asked, and that interested us a great deal, because if the prosecution wasn’t asking him those interesting questions, that suggested that there was a reason they weren’t, and the reason might be that they were trying to cover it up. Anyway, it took two days, and we got confirmation that there was, and in fact there was a slush fund of $750,000.

Failure is the most likely outcome of entrepreneurship. Hence there is absolutely nothing wrong with failure. It is the default outcome. Success on the other hand is rare and unpredictable. Very few find it. However what can help entrepreneurs succeed is when an ecosystem learns from failure.

No, no. Well, you know, biology is such a complex system. It’s totally different from the engineering. We cannot design. Many people tried to find the therapy for cancer, but all failed. And myself, I never expected my research, working on the immune system, would lead to the cancer therapy. But, in a sense, I’m very fortunate that I also thought about it. You know, you have to try many things and if you’re lucky you can hit, but you have to pursue. That’s my feeling.

Many people talk about a willingness to have failures. I hate failures. I don't think you should strike to make failures. I think it's OK to make mistakes – but by the time they become real failures, you probably should have discovered them much earlier.