The challenge of a big, over-arching vision is that it's hard to know where to start. And your biggest opportunity will change from year to year. Technology changes. Competition changes. You change. My advice: Just start. Find a single unmet need that nudges the world closer to where you believe it's going. And if you hit a dead end, pivot.

Your time is limited, so don't waste it living someone else's life. Don't be trapped by dogma — which is living with the results of other people's thinking. Don't let the noise of others' opinions drown out your own inner voice. And most important, have the courage to follow your heart and intuition. They somehow already know what you truly want to become. Everything else is secondary.

My advice to everyone is: “Become a journalist.” ... if you have a chance to be a newspaper reporter for three or four years — before you do whatever you want to do — do it, because you will know so much.

Well, I will bring this technology to clinics. I really want to help as many patients as possible. As you may know, I started my career as a surgeon 25 years ago. But it turned out that I am not talented as a surgeon

Failure is the most likely outcome of entrepreneurship. Hence there is absolutely nothing wrong with failure. It is the default outcome. Success on the other hand is rare and unpredictable. Very few find it. However what can help entrepreneurs succeed is when an ecosystem learns from failure.