The first principle is that you must not fool yourself—and you are the easiest person to fool. So you have to be very careful about that. After you've not fooled yourself, it's easy not to fool other scientists. You just have to be honest in a conventional way after that.

There's the world's work to be done, and there are never enough citizens with determined hearts, courageous character, intelligent minds, and idealistic souls to do it. Yes, our world already has quite enough guns, political platitudes, arrogance, disingenuousness, self-interest, snobbishness, superficiality, war, and the certainty that God is on one side or the other. But it never has enough conscience, nor enough tolerance, idealism, justice, compassion, wisdom, humility, self-sacrifice for the greater good, integrity, courtesy, poetry, laughter, and generosity of substance and spirit. It is these elements that I urge you to carry into your careers, and remember that the great game of life is not about money; it is about doing your best to build the world anew.

Do not despair of our present difficulties but believe always in the promise and greatness of America, because nothing is inevitable here. Americans never quit. We never surrender. We never hide from history. We make history.

The two things that I miss most when living out of Australia are the bush and the Pacific coast, especially fishing in the surf at night! My father had a workshop and I learned to be a carpenter, a skill that has resulted in the manufacture of some very substantial coffee tables and a fair amount of time working on houses.

On returning to Brisbane, I realised fairly quickly that I am an experimentalist at heart. A career as a diagnostic virologist was not for me!

I tried for a Ph.D. scholarship to work with Cedric Mims, but was told to apply again later because he already had a "scholar" and would take only one student at a time. … The following week a job in the Department of Experimental Pathology at the Moredun was advertized in Nature. We sailed for Britain in early 1967, on a very slow and cheap ship.