Her story is why I dedicate the Nobel Peace Prize money to the Malala Fund, to help give girls quality education, everywhere, anywhere in the world and to raise their voices. The first place this funding will go to is where my heart is, to build schools in Pakistan—especially in my home of Swat and Shangla.

When I started getting my first fan letters, I made a point to try to respond to every single one. The wins always felt that much more special because I knew I was making so many people happy. And losses hurt that much worse because I truly was invested in not wanting to disappoint those who supported my side. But more than anything, I always appreciated the fact so many fans invested their emotions in my performance.

My training took seven years. I didn’t learn how to make sushi for the first three years. I only got two days off a month, and slept on the restaurant floor. But I loved the job. I’d go to the fish market every morning. I got to open the restaurant and see the customers. I’d watch my mentor making sushi and would copy him under the table, practising with my fingers.

My science family came from all over the world, and members were of varied backgrounds, cultures, and abilities. The diversity in this "small world" I worked in daily provided the most stimulating environment, with many challenges and much optimism. Over the years, my research group has had close to 150 graduate students, postdoctoral fellows, and visiting associates. Many of them are now in leading academic, industrial and governmental positions. Working with such minds in a village of science has been the most rewarding experience – Caltech was the right place for me.

So Quigley taught a course called “The History of Civilizations,” and at the end, he said that the great gift of Western civilization to the human race was the idea of progress in a very specific way. He said it was the idea that the future can be better than the present and that every single person, not just the rulers, not just the elected leaders, not just the billionaires, every person has a personal moral obligation to make it so, to keep it going, to make the future better. And it resonated with me. I thought, “That’s the purpose of politics.” It made me really think even more than I had before that I might like a career in public service. It also made me aware of why in the aftermath of something like the 2008 crash you are going to have so much disorientation and anger and frustration because too many people have gotten up every day, and some still do, and looked in the mirror and thought all their tomorrows were going to be like yesterday. It’s the ultimate disempowerment. There’s nothing you can do for yourself, and even worse, for your family. It’s going to be all the same, and Quigley made us understand that our whole culture in Western civilization was designed to counter that, to believe that you personally could make a difference, and I never got over it.

We have all these interesting challenges now. No one knows whether automation and robotics, nanotechnology, will kill more jobs than it creates. If it does, that presents a serious problem. What are we going to do? Have a few of us work to support everybody else, or shorten the workweek for everybody? If so, how do we get from here to there? No one knows yet how we’re going to stop cyber terrorism from wrecking honest discourse in democracy and maybe putting our very lives at risk.

And I think it had something to do with my grandmother and my mother being nurses, and my mother once said to me, “Once you see people bleed it’s hard to believe there’s much difference in race.

Yeah. I’m the luckiest person who ever lived, you know? I worked hard, like a demon. Some would say too hard from time to time, and I over-married, and I had a magnificent child. I have been incredibly fortunate, but I had the American Dream, and it didn’t matter to anybody that nobody in my family had ever been to college.

I thought that I had lost for a reason, and I thought that I was a little unseasoned and immature, and I had — the way I made decisions my first term, I got a lot done, but I was better at doing what I wanted to do than listening to other people about what they thought I should be doing or how they thought I ought to be doing it.

Yeah, there were a lot of brave people who stood up. Then, you know, it cost Martin Luther King and Medgar Evers and the three civil rights workers in Philadelphia, Mississippi, and Viola Liuzza and a lot of the others their lives, but they were on the right side of history, and they believed if they made this sacrifice that it would work out. And whenever I get discouraged about everything they stood against rising up again, I realize there just are no public, or permanent, victories. You have to keep fighting for freedom.