So I decided I was going to invest my time. I spent Monday through Thursday at Frito-Lay, commuting from New York to Texas. Then Friday, Saturday and Sunday, I did my regular job in New York. It was an incredible commitment of time but it was an amazing developmental experience. It was challenging, broadening, and helped me reach the position I have today.

I think chess — actually, a number of things that I learned when I was young — it wasn't so much the chess itself; it was the skills that you were training while you were playing chess. So problem-solving, imagination, creative thinking, strategic thinking, all of these things — if you play chess to a high level, what you're really honing is those meta-skills. And I realized from quite young, that's one of the reasons I liked chess was this is a great practice for me to get good — sort of like a mental gym, if you like — to get really good at those other skills, which you could then translate to all sorts of other subjects like science or business.

However, it was very natural that a failed surgeon with little experience in molecular biology had a hard time finding a position. A turning point came when I got a fax from Thomas Innerarity at the Gladstone Institute of Cardiovascular Diseases in San Francisco. After a short telephone conversation, Tom was brave enough to give me a postdoctoral position in his lab! Working at Gladstone was one of the best decisions I ever made in my life.

My science family came from all over the world, and members were of varied backgrounds, cultures, and abilities. The diversity in this "small world" I worked in daily provided the most stimulating environment, with many challenges and much optimism. Over the years, my research group has had close to 150 graduate students, postdoctoral fellows, and visiting associates. Many of them are now in leading academic, industrial and governmental positions. Working with such minds in a village of science has been the most rewarding experience – Caltech was the right place for me.

I moved to Argentina, then back to Tokyo and then to Anchorage, in Alaska, where I ran a restaurant. After 50 days the restaurant burnt down – an electrical fire. I lost my dream. I lost my money. I lost my passion. I thought about suicide, but thinking of my family and my kids made me realise I had to wake up.