My wife, Nellie, my high school sweetheart. She helped me in so many ways. I suppose people today might say it’s hard to believe, but I was an extremely shy person. Maybe being raised in the country had something to do with it. She got me to go to take public speaking classes, which I probably wouldn’t have done. I know that was of great help to me. And then, in so many other ways. She was a year behind me in high school. I’ve got a picture of us when she was 15 and I was 16. I don’t know why but, when we met, it was just love at first sight. She is the only girl I ever went with. I was a year ahead of her and I went away to college. Then, she graduated from high school and worked, and we didn’t get to see each other that much because times were hard. Even though it’s only 70 or 80 miles from Lafayette to Burnsville, the bus might have been 10 or 15 cents. I didn’t have it and she didn’t either. We didn’t get together much but we knew as soon as I graduated and got a job, we would get married and we did. She was a tremendous influence in so many ways. I’d say that my college coach, Piggie Lambert, is one of the most principled persons I’ve ever known. He had a lot of effect on my life. The head of the English Department at Purdue University, Dr. Creek, took a liking to me and tried to get me to forget sports completely and just concentrate on becoming a college English professor. There was some sort of a scholarship that he could get me for graduate school, but, I wanted to get married and get a job. So, I’d say that my father and mother, I don’t want to neglect my mother, and my wife and Piggie Lambert, my college coach at Purdue, probably had more influence on what I became as a teacher. That’s all I was: a teacher. That’s all I was as a basketball coach, just a teacher.

In my early years it was undoubtedly my father. My father was director of a sanatorium for pulmonary tuberculosis, and at that time there were no antibiotics, tuberculosis was a terrible disease. And, he and I would walk in the woods around that sanatorium and he would discuss his worries about his patients. And from him, I certainly inherited this extreme concern about the well-being of patients. I’ve seen him very happy when he succeeded after months and months of rest and other things to have these people go home cured. I’ve also seen him crying and desperate after trying for a long time and a patient did not get well, and went home to die.

My father was a great educator for me. He taught me so many things. He named me Carlos after a brother he lost — a very brilliant young man who died at 21 in Mexico. He had written very good poems. He was an intellectual. I think my father wanted to see his brother in me, so he put books into my hands at a very early age. He fostered my literary and artistic inclinations. So he was my best teacher.

The closest to inspiration was my beloved fifth grade teacher, Mrs. Ponti, who I’m delighted lived long enough to get that book’s dedication. I exchanged Christmas cards with her for the rest of her life. She was a wonderful woman. I think the main way she inspired was by respecting students’ interests. She herself knew very little science. Science was not formally taught at all, as far as I can remember, at grade school level. She realized there were a group of us who were interested in science, so she would let us sit by ourselves in the back of the classroom once a week for a couple hours, and she got books for us and discussed science. So I suppose she was a very good model for good students.

It was a very important finding for us because we were involved in nucleic acids. There weren’t many people interested in nucleic acids. There weren’t many people who believed that was the way to find drugs. But when we found out the structure, and we began to understand what kind of bases could be incorporated, and which ones couldn’t, and where they could be incorporated, it put a whole new dimension on it. So it had a very significant effect.

I think I’m most proud of the fact that so many of the drugs have really been useful in saving lives. I’ve run into people whose lives have been saved, and the kind of satisfaction that you get from having someone come up and say, “My child had acute leukemia and your drug saved him.” Or, “My little girl had herpes encephalitis, and she is now cured, she is back at school. She is doing very well. People told me that she might be mentally affected, but she is not.” I run into people who have had kidney transplants for 20 years who are still taking the drug. And I don’t think that anything else that happens to you can match that type of satisfaction.