Gertrude B. Elion

I can’t remember that anyone in particular did. I think perhaps it was my mother who influenced me the most. She was a housewife. She had no higher education, but had the most common sense of anyone I knew, and she wanted me to have a career. So she was always very supportive, at a time when many women of her generation would not have been.

I think I’m most proud of the fact that so many of the drugs have really been useful in saving lives. I’ve run into people whose lives have been saved, and the kind of satisfaction that you get from having someone come up and say, “My child had acute leukemia and your drug saved him.” Or, “My little girl had herpes encephalitis, and she is now cured, she is back at school. She is doing very well. People told me that she might be mentally affected, but she is not.” I run into people who have had kidney transplants for 20 years who are still taking the drug. And I don’t think that anything else that happens to you can match that type of satisfaction.

It was a very important finding for us because we were involved in nucleic acids. There weren’t many people interested in nucleic acids. There weren’t many people who believed that was the way to find drugs. But when we found out the structure, and we began to understand what kind of bases could be incorporated, and which ones couldn’t, and where they could be incorporated, it put a whole new dimension on it. So it had a very significant effect.