Our culture lionizes entrepreneurs who navigate daring switchbacks in their career. Steve Jobs was admired not just for Apple, but also his detour to found Pixar. Elon Musk is revered for helming Tesla AND SpaceX. But don't be distracted by other people's winding paths. I believe you should celebrate your single-mindedness, and stick to your own overarching idea — for as long as it holds your own fascination. In my experience, that could last your entire career.

So, look, I read lots of books, lots of them, you know, especially when I went from programmer to a business, realizing I have to just learn business really quick. I got really dismayed with the quality of business books pretty quickly, because frankly, I think the business books are largely written by the people who have time, who are not the people who actually build companies, frankly.

Not very well. I try to win the next one. I've always been told that you should win and lose with a smile, but since I became a professional, I've thought the best way of learning to deal with defeat is not to lose.

I didn’t realize that scientists were like that, and that people were like that. I would have thought — and I like to hope — that I encourage people rather than discourage people. I think you can say no and still say, “Boy, that might be a tough problem, but if you really work at it maybe you’ll solve it,” rather than, “No, it will never happen.”

My parents tell me I was fascinated by numbers even at age two, when I tried teaching other kinds to count using number blocks.

Perhaps one character trait which does help is the ability to focus, and perhaps to be a little stubborn. If I learned something in class that I only partly understood, I wasn't satisfied until I was able to work the whole thing out; it would bother me that the explanation wasn't clicking together like it should. So I'd often spend a lot of time on very simple things until I could understand them backwards and forwards, which really helps when one then moves on to more advanced parts of the subject.