Get on with it. But make sure you do want to do it. I think that’s the important thing, to be something that you would enjoy. If you only just go into science to get rich or to win gold medals, then I wouldn’t bother, but if you really want to enjoy yourself in the lab, then do it.

Well, I will bring this technology to clinics. I really want to help as many patients as possible. As you may know, I started my career as a surgeon 25 years ago. But it turned out that I am not talented as a surgeon

And the most fulfilled, centered, grounded, happy people I know are people who made the choice to be part of an effort to actually make the world a better place. ... I would say, to me, the path of least regrets is to at least make a short-term commitment to say, “Let me work to make a real difference in the world.” The worst that could happen is you decide to move into something else later, but you’ll always take with you what you’ve given and what you’ve gained through that experience.

Every kindness I received, small or big, convinced me that there could never be enough of it in our world. To be kind is to respond with sensitivity and human warmth to the hopes and needs of others. Even the briefest touch of kindness can lighten a heavy heart.

I’ve been mortally opposed to the so-called life-and-death committees that were instituted. When there were many more patients that needed to be dialyzed, and not enough artificial kidneys available, you had the institution of the life-and-death committees. ... Depending on the answer to these questions, he could be dialyzed. Otherwise, he could go to hell. I’ve been mortally opposed to that. When I set up a dialysis center here with a grant from some government agency, I was forced to put in a life-and-death committee, but it never met.

No. You see immediately what your next task will be. I’ve been asked all kinds of silly questions, like “Aren’t you proud? Aren’t you this? Aren’t you that?” I have no time for that, because the next project is upon me.

When I was this young assistant at the University of Groningen my responsibility was for four beds, or rather the patients in four beds. That was all I had to do. And, one of these patients was a young man, 22 years old, who slowly and miserably died from renal failure. He became blind, he vomited, and it was a miserable death. And I, as a very, very young physician, had to tell his mother, in a black dress and a little white cap like the farmers have, that her only son was going to die. I couldn’t do a damn thing about it. So, I began to think, “If I could just every day remove as much urea as this boy creates, which is about 20 grams, then the boy could live.” Well, he died, but I began to work on that.

In my early years it was undoubtedly my father. My father was director of a sanatorium for pulmonary tuberculosis, and at that time there were no antibiotics, tuberculosis was a terrible disease. And, he and I would walk in the woods around that sanatorium and he would discuss his worries about his patients. And from him, I certainly inherited this extreme concern about the well-being of patients. I’ve seen him very happy when he succeeded after months and months of rest and other things to have these people go home cured. I’ve also seen him crying and desperate after trying for a long time and a patient did not get well, and went home to die.