What is the best advice you have ever received?

If I were to give advice to young people, high-achieving young people for example, I'd have to say, don't neglect your family. Politics is important, sitting at the head table is glamorous. Traveling around the world, trying to do something for world peace was wonderful. But family and friends and faith are what really matter in life. And I know that. I see it so clearly now. And so, as they climb the ladder of achievement, I'd simply say, remember what Barbara Bush told those girls at Wellesley: "What happens in your house is more important than what happens in the White House." And it's true. It's so 100 percent true.

wisdom acquisition is a moral duty. It’s not something you do just to advance in life. Wisdom acquisition is a moral duty.

Her lesson all the time was “To them to whom much has been given, of them will much be required.”

I often repeat to them something that — not my mentor, but a senior scientist at the NIH — said to me once. We were having lunch together. I was despondent, despondent because nothing had worked. I had been there a year. And this guy said to me, “Look,” he said, “do you know the difference, Bob, between an average scientist and a world class scientist?” I said no. He said, “Here’s what it is.” He said, “For the average scientist, maybe one percent of their experiments work. But for the world class guy, the world beater, it could be as high as one-and-a-half or two percent.” And then that really stuck with me because it’s really true.

My mother-in-law’s advice, which she gave me on the day of our wedding — we were married in Marty’s home, and his mother took me into the bedroom, her bedroom and said, “Dear, I’d like to tell you the secret of a happy marriage.” “Yes. What is the secret?” “It helps sometimes to be a little deaf.” And I found that advice — it stood me in very good stead not only in a wonderful marriage that lasted well over half a century, but in every workplace I’ve served, dealing with my faculty colleagues when I was a law teacher, and even now with my colleagues on the Supreme Court. When an unkind word is said, a thoughtless word, best to tune out.

And I never forgot what he said, Bill Clinton. He looked at me, and he said, “You know, Leon, you can be the greatest OMB director in the history of the world, but nobody’s going to remember you if the White House has fallen apart!” I never forgot that.

Harold Prince went to see it and he wrote me a letter saying don’t be discouraged about this because actually there’s some quite good songs in here. But he also said something which stayed with me all my life, which is that you can’t listen to a musical if you can’t look at it, by which he was actually saying that the designs for Jeeves were absolutely hideous.

The best advice I got from a painter friend of mine when I said, “If you had one thing to say to an aspiring artist like myself, what would you say?” And she said, “Make as many mistakes as you can.”