How has a failure, or apparent failure, set you up for later success? Do you have a favourite failure?
Recorded Christiane Nüsslein-Volhard said elsewhere, not written here
As I was lazy and rarely did my homework, I finished high school with a rather mediocre exam. I almost did not pass in English language. Recently, my previous teachers allowed me to see their report on my high school performances, which included the following statements: Despite the fact that her talents are rather equally spread among many areas of knowledge, her performances are rather different depending on the distribution of her interests. Thus, with her strong display of self will she can be decidedly lazy in some topics over years, while in her areas of interests she performs to a degree far extending that required for normal school purposes.

Laureate-written autobiography for Les Prix Nobel, Nobel Prize Outreach, 1 December 1995 source ↗

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Frederick Sanger Biochemist; twice a Nobel laureate in Chemistry, 1958 and 1980
They’re not failures, you try something and it doesn’t work, and some people, you know, get fed up with this, and I’ve known some of my friends and colleagues who have just decided to give up science because they can’t stand it, but I’ve always decided, you know, if it doesn’t work, forget it and start planning the next experiment, and that’s always exciting.
Recorded Academy of Achievement interview, 28 October 2000 source ↗
David Lynch Film director, screenwriter and painter
But there’s always a way. Sometimes restrictions are a big blessing.
Recorded Carol Diehl, Interview Magazine, 25 January 2012 source ↗
Chimamanda Ngozi Adichie Novelist and essayist
But after one year of medical school I fled. I realized I would be a very unhappy doctor and I really did not want to be responsible for the inadvertent death of my patients. Leaving medical school was a very unusual decision, especially in Nigeria where it is very difficult to get into medical school. Later, people told me that it had been very courageous of me, but I did not feel courageous at all. What I felt then was not courage but a desire to make an effort. To try.
Recorded Wellesley College 137th Commencement, 29 May 2015 source ↗
Kurt Vonnegut Novelist and essayist
I would try to write my war story, whether it was interesting or not, and try to make something out of it. I describe that process a little in the beginning of Slaughterhouse Five; I saw it as starring John Wayne and Frank Sinatra. Finally, a girl called Mary O’Hare, the wife of a friend of mine who’d been there with me, said, “You were just children then. It’s not fair to pretend that you were men like Wayne and Sinatra, and it’s not fair to future generations, because you’re going to make war look good.” That was a very important clue to me.
Recorded George Plimpton, David Hayman, David Michaelis and Richard Rhodes, The Paris Review, issue 69, Spring 1977, 1 January 1977 source ↗

More from Christiane Nüsslein-Volhard

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Question What is the most important lesson life has taught you? Time & hindsight
Not really. I thought that getting the Nobel Prize was a big interruption in my career, I thought and it was very distracting. It takes a lot of time you know, it just takes time to be honoured, you have to travel and you have to give speeches of things you have, oh it’s so often that you get bored to tears when you hear your own voice. And it’s really taking a lot of your time and there’s no way that during this time you can start something new, I mean you just profit from what you’ve done and there is no time to develop new ideas.
Recorded Marika Griehsel, Interview at the 53rd Lindau Nobel Laureate Meeting, 30 June–4 July 2003, Nobel Prize Outreach, 1 July 2003 source ↗
Question What inspires you to learn? Attention & the world
I think a very big curiosity. I’m very curious and I like to understand things and not only science but also other things where I just try to find out why things work or how things work. Science and nature caught my attention as a small child already. I was growing up in a city but we had a garden and I loved the garden and then often on vacation I was at a farm and I loved these animals and plants and so on, so I was attracted very early on and then we had a very good teaching actually at my … I don’t know whether my teachers really had much of a role because I was determined very early, but then I also did music and I did languages and Literature and so on. I have broad interests actually other than science, but this is really true, this curiosity.
Recorded Marika Griehsel, Interview at the 53rd Lindau Nobel Laureate Meeting, 30 June–4 July 2003, Nobel Prize Outreach, 1 July 2003 source ↗
Question Which teacher, parent, coach or friend most made you who you are, and what did you learn from them? Relationships
we had a wonderful education because my parents were so practical … Christiane Nüsslein-Volhard: Yes I mean, I have a strong likeness of culture and also I mean my grandmother was a painter and we do music in the family quite a lot and I think that’s very important. What was also important, I thought about that recently, also maybe as a follow-up of an interview but I was asked what my parents did and so on and looking at my brothers and sisters, we had a wonderful education because my parents were so practical, they did books themselves and we did a lot of handicrafts and I knew how to knit and sew and cook and we learnt a lot to do things ourselves, to make things ourselves so we all have some dexterity in doing things ourselves and this is also very important for Science
Recorded Marika Griehsel, Interview at the 53rd Lindau Nobel Laureate Meeting, 30 June–4 July 2003, Nobel Prize Outreach, 1 July 2003 source ↗
Question What is something everyone in your world agrees about that you think is wrong? Values & belief
I continued the work on dorsal, discovered the recessive phenotype and interpreted the phenotype postulating a gradient determining the dorsoventral axis. At that time, gradients were not widely accepted as mechanisms, in particular biochemists were highly sceptical, however the Tübingen influence made such models attractive to me.
Recorded Laureate-written autobiography for Les Prix Nobel, Nobel Prize Outreach, 1 December 1995 source ↗

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