I have never made any money from my films but I have won prizes and recognition. I have been on the margins forever. They all came to see me receive the award - there was Tom Hanks, Steven Spielberg and Richard Gere and so on. I was imagining what they would all be worth in money terms. You see I was never bankable, I could not bring any money ever to the table. I like the friendships and, yes, the admiration but I don’t want to make a big fuss about it. I will go on working as long as I am able!

When I lost that 100m final I spiralled. I went quite aggressive. It is an Adam I don't really recognise.

No, no. Well, you know, biology is such a complex system. It’s totally different from the engineering. We cannot design. Many people tried to find the therapy for cancer, but all failed. And myself, I never expected my research, working on the immune system, would lead to the cancer therapy. But, in a sense, I’m very fortunate that I also thought about it. You know, you have to try many things and if you’re lucky you can hit, but you have to pursue. That’s my feeling.

Whenever you’re making a movie, especially when you’re writing, you always have self-doubts. I did the first location shooting in Tunisia.

I strongly feel that this is, that I am able to receive this award because of John Gurdon and also many other researchers in the field. This field has a long history, starting with John Gurdon. So I feel very lucky. I may have played some important role in this long history, but it was not myself who initiated this field. So that’s my feeling right now.

A book also pushed me to become a medical doctor. I was deeply inspired by Torao Tokuda, a physician who founded a hospital group in the 1970s that tried to revolutionize the Japanese medical care system.

Well actually I was at home. I was doing some housework. So I was very surprised.

However, it was very natural that a failed surgeon with little experience in molecular biology had a hard time finding a position. A turning point came when I got a fax from Thomas Innerarity at the Gladstone Institute of Cardiovascular Diseases in San Francisco. After a short telephone conversation, Tom was brave enough to give me a postdoctoral position in his lab! Working at Gladstone was one of the best decisions I ever made in my life.

my second failure in my career. But that second failure got me interested in knockout mice, mouse technology. So I think failure is important in my career

Running CiRA with some 250 staff, I have come to spend less time discussing their data with my colleagues and students, and have been absorbed by my duties as the "chief executive officer" of CiRA, including devising strategies to advance both basic and applied research and to obtain sufficient funding. Anxious about the lack of financial resources for the future to allow us to continue hiring research support staffers, I even ran the full Kyoto Marathon in 2012 to raise online donations from the public. It was hard but helped us raise more than 10 million yen.