If you go into the field of medicine, I think any, very active protein like, let’s say interferons have been isolated, thanks to these techniques and then the question was, how should one apply them? In which kind of medical problems? Some, there were some deceptions but there were also discoveries that in certain other fields these products were very useful. Another example which has been widely successful is the product of human insulin which made medicine largely independent of insulins harvested from living animals and I think if one looks at these things these are really very good examples.

Mr. Rogers lives on. There’s so many legions of people that grew up with him, and they’re still in a way growing up with him. He, of course, was a minister. ... And the children of the show, in the neighborhood, are his ministry. And what a beautiful thing that is. So I, to this day, when someone says, “What are you most proud to have accomplished?” I am so proud to have been a part of that.

Probably my family in terms of kids I've got, my mum and dad, the whole network of family. I'm really close with my aunties, uncles, nans, grandads, trying to spend as much time together as possible, so I'd say that's one thing I'm really proud of, that I have a loving family.

I think three things. One is the great advances in auto safety. I mean, there are tens of thousands of people being saved every year because cars are safer, and millions of people over a decade, injuries prevented. I think that’s a good example of the need to make technology more humane. We may benefit from a lot of technologies, but they exact a cost. Emphysema, cancer, soil contamination, contaminated water, death and injury on the highway. We’ve got to put more effort on making them more humane.

So I think failure is important in my career.

Well, I will bring this technology to clinics. I really want to help as many patients as possible. As you may know, I started my career as a surgeon 25 years ago. But it turned out that I am not talented as a surgeon

In Japan, however, I found myself suffering from Post America Depression or PAD. The environment for researchers in Japan was quite different in many ways from that in the U.S. At the medical school, very few scientists showed interest in the basic biology of mouse ES cells, and there was little thought-provoking discussion with my colleagues. Some of my colleagues advised me to work on something more related to medicine. Furthermore, I could not get enough funding and had to change the cages of the numerous mice by myself every week. What was worse, the Nat1 work was being rejected by many journals. I felt lonely and depressed, and I was about to give up my career as a scientist and return to the path of physician.

I was born in Osaka, Japan. It was 45 years ago. My father has a small factory in Osaka, and we lived next to his factory

Running CiRA with some 250 staff, I have come to spend less time discussing their data with my colleagues and students, and have been absorbed by my duties as the "chief executive officer" of CiRA, including devising strategies to advance both basic and applied research and to obtain sufficient funding. Anxious about the lack of financial resources for the future to allow us to continue hiring research support staffers, I even ran the full Kyoto Marathon in 2012 to raise online donations from the public. It was hard but helped us raise more than 10 million yen.

Well actually I was at home. I was doing some housework. So I was very surprised.