you have got to be totally honest and give advice and analysis that you’re asked to give that’s based on evidence. And if the analysis that you come to comes to a conclusion that a president might not like to hear that, you can’t be afraid of saying, “Mr. President, with all due respect, this is the way I think the situation is.”

I’ve had this concern all the time, but I can only hope that if one writes with appreciation and delicacy and respect, then it’s okay. I have to say that I’ve written a hundred times as much as I’ve published, because if there’s any thought of offense or embarrassment, then I will put the thing quietly away.

These tics do bother me. Could I play a match without them? Yes, without some of them. I don't have to touch my nose or put my hair behind my ears before I serve. That's possible to stop. Not putting the bottles in front of my chair, I could go without that, too. But adjusting my underwear, that I could never get rid of. It's impossible.

That’s a very good question. I think I’m a very lazy writer and by that I mean that I do not battle, I don’t struggle too hard against it. If I have difficulties in the writing, I just go and do other things. I don’t feel a compulsion to write. Of course, when I start writing then it becomes a compulsive activity, because I’ve begun something and I want to continue, want to finish it. … I know there are other writers who sit down religiously every morning, they take their espresso, they put a clean sheet of paper there and they sit looking at that paper until they’ve finished or covered at least a number of those pages. No, I’m not like that. I have to be ready. It has to gestate it for quite a while and then it’s ready to burst forth.

we know the fish, we know the worm, we know the fly, but we don’t know the links between and we don’t know, when we go back to the branches in evolution, we really don’t know what happened there when they branched and how they divert and what is the major drive for evolution.

I felt at the time that Eric was much more successful than I, he was extremely productive during his time in Zurich, and worked on many very original projects, germ line, cell lineage, sex determination, where not many people could follow him. I also had the impression that I was dependent on him because he had more fly experience and without him I would not have gotten the job. This made our start in Heidelberg a little difficult, until we sorted things out, and from then on we thoroughly enjoyed working in the same lab.

I think a very big curiosity. I’m very curious and I like to understand things and not only science but also other things where I just try to find out why things work or how things work. Science and nature caught my attention as a small child already. I was growing up in a city but we had a garden and I loved the garden and then often on vacation I was at a farm and I loved these animals and plants and so on, so I was attracted very early on and then we had a very good teaching actually at my … I don’t know whether my teachers really had much of a role because I was determined very early, but then I also did music and I did languages and Literature and so on. I have broad interests actually other than science, but this is really true, this curiosity.

so I sometimes think, why should I talk young women into being a scientist if they then end up being sort of disliked or not accepted by their contemporaries and so it’s a tricky business actually.

I immediately loved working with flies. They fascinated me, and followed me around in my dreams.

I continued the work on dorsal, discovered the recessive phenotype and interpreted the phenotype postulating a gradient determining the dorsoventral axis. At that time, gradients were not widely accepted as mechanisms, in particular biochemists were highly sceptical, however the Tübingen influence made such models attractive to me.