One of the saints in my life is this woman named Imogene Hill, who was a fourth-grade teacher who taught this advanced class. She got hip to my whole situation in about a month and kindled a passion in me for learning things. I learned more that year than I think I learned in any year in school.

The questions of the students are often the source of new research.  They often ask profound questions that I’ve thought about at times and then given up on, so to speak, for a while.  It wouldn’t do me any harm to think about them again and see if I can go any further now.  The students may not be able to see the thing I want to answer, or the subtleties I want to think about, but they remind me of a problem by asking questions in the neighborhood of that problem.  It’s not so easy to remind yourself of these things.

I got very interested in so-called “knockout mouse” technology. Knockout mouse is a way to study the function of genes. You know, both human and mouse have approximately 20,000 genes. With knockout mouse technology, we can select one gene out of those 20,000 genes, and completely destroy that one particular gene so that we can understand the function of that particular gene. I got very interested in that technology. It was 1992 or 1993 when I graduated from my Ph.D. school. So I decided to study — I decided to learn about knockout mouse technology. But at that time in Japan, only a few scientists were working on knockout mouse technology. That’s why I decided to move to the States, San Francisco

Ultimately, it’s a man who was teaching us English Literature in what we call matricula, the last 2 years of high school. He really was quite extraordinary. When he spoke of a Shakespearean play, you almost thought that he grew up with Shakespeare! He was very good, yes. A black guy who was fantastic and gave us a deep love for literature.

I sing yes sure and I garden, I have a large garden and I really recreate myself by doing gardening and thinking about something else so that when your mind gets free from all the burden of the daily troubles and then you can start putting something fresh in, you know.

Not really. I thought that getting the Nobel Prize was a big interruption in my career, I thought and it was very distracting. It takes a lot of time you know, it just takes time to be honoured, you have to travel and you have to give speeches of things you have, oh it’s so often that you get bored to tears when you hear your own voice. And it’s really taking a lot of your time and there’s no way that during this time you can start something new, I mean you just profit from what you’ve done and there is no time to develop new ideas.

we had a wonderful education because my parents were so practical … Christiane Nüsslein-Volhard: Yes I mean, I have a strong likeness of culture and also I mean my grandmother was a painter and we do music in the family quite a lot and I think that’s very important. What was also important, I thought about that recently, also maybe as a follow-up of an interview but I was asked what my parents did and so on and looking at my brothers and sisters, we had a wonderful education because my parents were so practical, they did books themselves and we did a lot of handicrafts and I knew how to knit and sew and cook and we learnt a lot to do things ourselves, to make things ourselves so we all have some dexterity in doing things ourselves and this is also very important for Science

As I was lazy and rarely did my homework, I finished high school with a rather mediocre exam. I almost did not pass in English language. Recently, my previous teachers allowed me to see their report on my high school performances, which included the following statements: Despite the fact that her talents are rather equally spread among many areas of knowledge, her performances are rather different depending on the distribution of her interests. Thus, with her strong display of self will she can be decidedly lazy in some topics over years, while in her areas of interests she performs to a degree far extending that required for normal school purposes.

so I sometimes think, why should I talk young women into being a scientist if they then end up being sort of disliked or not accepted by their contemporaries and so it’s a tricky business actually.

I don’t think it’s misused yet, people are afraid of it might be misused but on the other hand, there is also value in finding out about the relation between several particular predispositions. You might be more careful if you are told that your genetic background is such that you shouldn’t eat fat in large amounts or so, it does help you change your life a little bit and so it’s not so bad, but it’s hard to find out which genetic background is causing these things.