I have also benefited from teaching; as I try to explain my views to students with critical and open minds, I find myself continually being challenged to go back and rethink ideas. I now see teaching and research as complementary, mutually reinforcing activities.

One of the saints in my life is this woman named Imogene Hill, who was a fourth-grade teacher who taught this advanced class. She got hip to my whole situation in about a month and kindled a passion in me for learning things. I learned more that year than I think I learned in any year in school.

I wanted to know. I asked a lot of questions and she would say, "Read, read."…So she inspired me a great deal.

I got very interested in so-called “knockout mouse” technology. Knockout mouse is a way to study the function of genes. You know, both human and mouse have approximately 20,000 genes. With knockout mouse technology, we can select one gene out of those 20,000 genes, and completely destroy that one particular gene so that we can understand the function of that particular gene. I got very interested in that technology. It was 1992 or 1993 when I graduated from my Ph.D. school. So I decided to study — I decided to learn about knockout mouse technology. But at that time in Japan, only a few scientists were working on knockout mouse technology. That’s why I decided to move to the States, San Francisco

I know that for a very long time my consuming passion, which was confirmed when I contracted TB — I had TB when I was about 12 or so — was I wanted to be a physician and when I got TB I was even more determined. I want to be physician so that I can find a cure for the scourge. And, in fact, I was admitted to medical school. If we had had the funds maybe today I would have been a physician.

I used to be “Mister Disinvestment.” Now I would like to be Mister Investment and say, “Come! Come and be part of an exciting, exhilarating process. Come in! Come in on the ground floor and see a people do something that’s probably never happened before, people seeking to become something radically different from what their antecedents would have made us believe they were likely to become.

I sent off the letter. I probably made a technical mistake by giving it to a journalist before hearing from the Prime Minister because this journalist was working for a Sunday newspaper and gave it enormous press, and I think quite rightly the Prime Minister was annoyed that I had not given him the opportunity but never mind.

Many of us had moments when we doubted that apartheid would be defeated, certainly not in our lifetime. But, I never had that sense. I knew in a way that was unshakable, because you see, when you look at something like Good Friday, and saw God dead on the cross, nothing could have been more hopeless than Good Friday. And then, Easter happens, and whammo! Death is done to death, and Jesus breaks the shackles of death and devastation, of darkness, of evil. And, from that moment on, you see, all of us are constrained to be prisoners of hope. If God could do this with that utterly devastating thing, the desolation of a Good Friday, of the cross, well, what could stop God then from bringing good out of this great evil of apartheid? So, I never doubted that ultimately we were going to be free because ultimately, I knew there was no way in which a lie could prevail over the truth, darkness over light, death over life.

Remember that the resentment and the anger leveled at the United States is not leveled against Americans as Americans. It is leveled against a particular policy followed by a particular administration, and change the policy or maybe change the administration, and you will find, I mean, that there is very little anti-Americanism in the world. There is a lot of — I mean, there is a lot of anger at an America that has been arrogant and an America that believe it is good, go it alone. You know, your unilateralism where you went to the United Nations thinking that they would just endorse your view, and when they said no, you said go jump in the lake, and you went and you did your own thing, and you landed in a huge mess. Well, people don’t want to say we told you so, you know, because you realize, I mean, after 9/11, most of the world was deeply — I mean, America was held in the highest. People really felt deeply for you, and I’m sure you all felt loved, and you dissipated it in next to no time. You know, I mean, chop, chop, chop, and it disappeared, but it shows, you know, it isn’t that there is an ingrained hatred of America. There isn’t.

But the thing I think that thrust me possibly into the public consciousness, I had just been elected Bishop of Lesotho. I had gone there to become bishop and I went for a retreat. I don’t know — I mean, I don’t know what happened but it just seemed like God was saying to me, “You’ve got to write a letter to the Prime Minister.” And the letter wrote itself.