So why do I talk about the benefits of failure? Simply because failure meant a stripping away of the inessential. I stopped pretending to myself that I was anything other than what I was, and began to direct all my energy into finishing the only work that mattered to me. Had I really succeeded at anything else, I might never have found the determination to succeed in the one arena I believed I truly belonged. I was set free, because my greatest fear had been realised, and I was still alive, and I still had a daughter whom I adored, and I had an old typewriter and a big idea. And so rock bottom became the solid foundation on which I rebuilt my life.

In fact, what I usually say to people, “Probably some of the most successful scientists are the ones that know how to deal with failure well.” Because it’s easy to feel good when you succeed. That’s an easy thing. But you’re probably going to fail in science a lot more than you succeed, so you really have to learn how to deal with it and not let it beat you.

I was prepared to fail. I was prepared to not be able to get things accepted, because I saw that happen to my mother.

As hard as it's been to come to this decision, I am at peace with it. I have no regrets. I was not supposed to be here in the first place, remember? Not many people believed in my talent and my abilities, yet I found a way to persevere, to prove them (and sometimes myself!) wrong.

Elliot, he has such passion for what it was we were doing that he instilled that passion in me. He was like, “Just go for it. Make it happen.” And I would give him some wild idea, and he’d say, “Go try it.” It was that next set of just knocking down the fear of failure. Just go try anything.

every time I heard the word “smart” attached to anything, it means it’s pretty dumb, because no one knows what it really does. They just add “smart” as a prefix to say, “Oh, you must buy this, because it’s smart.” If they can’t tell you what it does and why it does it, don’t buy it just because it says “smart.”

Learn by doing, not learn first, then do. The way you discover what it is you like to do in life is by doing first, then learning about it.

I regularly gift the book called In Praise of Shadows .