There were lots of times, especially in the early days, that were very, very difficult. I think the most difficult experience I had was in 1990 when Oracle had its only loss quarter in history. We’d been in business for 20 years, and after 20 years we lost money one quarter. We had a very difficult time. We had virtually doubled our sales every year for ten years. Nine out of ten years, ten out of eleven years. It was really quite an amazing run. We were the fastest growing company in history

Very often I had to fight for the recognition of my ideas, particularly since, in those earlier days, I wasn’t in any prominent position where people would listen to me.

I do think my mother had a lot to do with that. I mean, after all, you know her — it was not near as bad as having your husband die in a car wreck after — he survives World War II. They had a great life planned, and he gets killed in a car wreck, not because of a concussion, but because in a fluke, the tire blows out on his car. He’s thrown out of the car. He lands in a ditch in a field, and the ditch is full of water, and he can’t get out of the ditch before he drowns. There’s — it made it look a little whiny for me to be all bent out of shape about losing an election, and I realized that it was a weird deal. It was 1980. It was Reagan’s election. It was a period not unlike now, widespread resentment over the stagnant economy, the Iran hostage crisis, and I bet I had a hundred people coming to — I’m not exaggerating — coming to me and saying, “God, Bill, I didn’t know you were going to lose. I just voted against you to because I didn’t like some of the things you’d done.” And I remember once — one of the funniest things that ever happened to me. I was driving over to see my mother. I lived in Little Rock, and she lived in Hot Springs 50 miles away, and in the middle of the trip was a little country store owned by a guy who ran the elections in that area and was real smart, so I went in to get a Coke, and started talking to him. And this little boy came up to me in overalls, and he said, “You’re Bill Clinton, aren’t you?” I said, “Yes.” He said, “I helped to beat you. I cost you 11 votes, and it was no accident.” I said, “You did?” He said, “Yeah.” He said, “It was me, my wife, our two boys and their wives, and five of my friends. We just decked you.” I said, “Why’d you do it?” He said, “I had to because you raised my car tax. The car license.” And so we’re standing on the interstate. I said, “Look over there. You remember when I was governor? That highway broke wide open, and even big trucks were off in the ditch, and I had to send the National Guard down here to clean it up, and we had to fix it.” He said, “Yeah, I remember. I don’t care. I still didn’t want to pay it.” So I was laughing at the guy, and I said, “Let me ask you something.” I said, “If I ever ran again, would you vote for me?” He said, “Absolutely.” I said, “You would?” He said, “Sure. We’re even now.” And I went — and there were no cell phones, so I had a dime. I went and put it in the payphone, and I called Hillary, and I said, “You know, I’m not dead yet. We might have to run again.

Adam, if you know about 10 years ago, I was here in October because I was kicked out, from Penn, was forced to retire. Then my husband supported me and said that, you know, when finally visited in Germany and found that maybe BioNTech is the right place, then he said "Just try it and I will make sure that you don't regret." Looking back in my life he supported that I would go, and for nine years I commuted to BioNTech in Germany. I did all these experiments actually, with my own hands, I was 58 years old, I was still culturing plasmids and feeding cells, so it is very unlikely.

I can always remember, when I was at high school we had a school sort of army battalion and because, at that time, I was one of the larger boys, I was appointed sergeant of the number one platoon, and I was always absolutely petrified that when I was meant to turn the platoon left or turn it right, I was really actually hopeless at knowing quite what to do. But fortunately, my platoon, who were really all the misfits in the school, the larger misfits, they stood by me, and some of them were quite good at knowing when to turn left or turn right. So whatever command I gave, they would do the right thing. We were a pretty good platoon as a consequence although, at the time, I felt an absolute idiot.

I would advise them to aim high. To set their sights at a pretty tough target and don’t be too worried if you’re not successful at first. Just keep persisting and keep improving your standards, getting better and better and ultimately, you’ve got a pretty fair chance at achieving your desired goal. ... But, I do think that virtually everybody that’s born has the ability to be very competent at doing something. I think that, in itself, is worthy of aiming towards, just to be competent at doing anything you particularly wish to do.

I still regard adventure pretty much as a hobby to tell you the honest truth, and I think this approach to it keeps one refreshed almost. I think if you just regard adventure as a business, working becomes very boring as many other businesses can become. But even though adventure changed my life considerably, both in what I was doing and even economically, I’ve always regarded myself in a sense as a competent amateur.

My mother used to say to me a thing which, when I look back on it, wasn’t terribly logical. — and I had a pretty hearty appetite, but when I had had a large meal put in front of me, and even I couldn’t get through it, she would say, “Edmund, remember the starving millions in Asia.” Now what possible use my consuming it would do for the starving millions in Asia, I don’t really know, but the fact remains that I was brought up to think about the starving millions in Asia. That meant I had to clean my plate up and not waste it. Later on, I got more involved with the starving millions in Asia, perhaps in a slightly more practical way: helping some of them with schooling and hospitaling and even in agriculture.

As I’ve gotten older, my goals have become more solidified. My main concentration is on the welfare of the people I’ve worked with in the Himalayas and on human welfare in general. I’m also extremely interested in the environment and trying to encourage people to be more concerned about what we’re doing to our world. Now I’m just one of thousands and thousands of people who have these same views these days. I think this is one of the great steps forward we’ve seen in modern decades — the considerable growing interest that people have in the environment and in keeping it reasonably clean and wholesome. I certainly hope it remains that way.

I really had no idea whatsoever. I feel that my life developed as I went along. I was never one of those people who, at an early age, had picked an objective and worked steadily towards it. All I knew was that I wanted to get involved in adventurous activity. I didn’t have any specific type of activity in mind, but I wanted to do things that were exciting and adventurous. I had a fairly diffused feeling as to what precisely it should be.