I got very interested in so-called “knockout mouse” technology. Knockout mouse is a way to study the function of genes. You know, both human and mouse have approximately 20,000 genes. With knockout mouse technology, we can select one gene out of those 20,000 genes, and completely destroy that one particular gene so that we can understand the function of that particular gene. I got very interested in that technology. It was 1992 or 1993 when I graduated from my Ph.D. school. So I decided to study — I decided to learn about knockout mouse technology. But at that time in Japan, only a few scientists were working on knockout mouse technology. That’s why I decided to move to the States, San Francisco
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Shinya Yamanaka
Stem cell biologist; Nobel laureate in Physiology or Medicine, 2012
Japan · b. 1962
Science and medicine
About
Physician and stem cell biologist, director of the Center for iPS Cell Research and Application at Kyoto University. Trained as an orthopaedic surgeon before turning to basic research, and shared the 2012 Nobel Prize in Physiology or Medicine with John Gurdon for the discovery that mature cells can be reprogrammed to become pluripotent.
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