Well, you know, the genotype. I'll mention something that nobody ever mentions. Let's say you have now a genotype that makes a certain protein. And that protein, and you can see this in every issue of Science practically, that protein is a very complex structure, incredibly complex. Now how that step from a group of amino acids to that polypeptide [happens] is an enormous jump. I think right now everybody leaves it alone because nobody yet has figured out just exactly how to attack this problem.

We still don’t understand the way a protein folds the way it does. I mean it’s an amazing thing.

I sometimes I have the inability to see how I can do what I need to do at a high enough level for me to do it.

we can select one gene out of those 20,000 genes, and completely destroy that one particular gene so that we can understand the function of that particular gene. I got very interested in that technology. It was 1992 or 1993 when I graduated from my Ph.D. school. So I decided to study — I decided to learn about knockout mouse technology. But at that time in Japan, only a few scientists were working on knockout mouse technology

I introspect a lot and keep asking myself questions on what is right and wrong.

When we develop blockbuster novel products and the world sits up and takes us seriously, then I would probably sleep peacefully.

Then, I would have made a difference to humankind. That will be the legacy I would like to leave.

I guess my learning about regulatory strategies is much better now, and I may have designed many clinical trials differently - for example, oral insulin.

I am very impatient, impulsive, proactive and often act in haste.

But this is a herd-like mentality as they only back e-tailing and not life science ventures based on genomics et cetera.