There are many battles. There’s so much that needs to be done. We need to protect the environment. Save this little planet. Not just this little piece of real estate we call America, but save the planet.

Well, I think the most single important issue today is to make sure that nuclear weapons will not proliferate beyond the eight, or nine, countries that already have nuclear weapons; and absolutely make sure that none of these nuclear weapons or this nuclear material will fall into the hands of any extremist or terrorist group, because if they got hold of this material, they would use it. That would be the beginning of the end for civilisation as we know it.

We still have a long way to go, we still have many obstacles and many challenges to face. It’s far from perfect, and it may never be, but I think as long as we do the best we can to improve conditions, then people will be benefited.

I certainly want to continue trying to understand how the global environment functions. The earth as a system is a very complicated one. And to understand it, we need very many disciplines, very many different scientists working together. I want to continue working with my specialty, which is chemistry, with the atmosphere. There is still much to learn about chemical reactions that occur out there in the air, in the atmosphere. So one of my projects now is to really learn more about this pollution that occurs in cities and that is spreading more through the globe. To learn it in enough detail so we can better tackle it, we can better come up with new ways of using energy, for example, that are not so damaging to the environment.

I strongly feel that this is, that I am able to receive this award because of John Gurdon and also many other researchers in the field. This field has a long history, starting with John Gurdon. So I feel very lucky. I may have played some important role in this long history, but it was not myself who initiated this field. So that’s my feeling right now.

I was born in Osaka, Japan. It was 45 years ago. My father has a small factory in Osaka, and we lived next to his factory

I got very interested in so-called “knockout mouse” technology. Knockout mouse is a way to study the function of genes. You know, both human and mouse have approximately 20,000 genes. With knockout mouse technology, we can select one gene out of those 20,000 genes, and completely destroy that one particular gene so that we can understand the function of that particular gene. I got very interested in that technology. It was 1992 or 1993 when I graduated from my Ph.D. school. So I decided to study — I decided to learn about knockout mouse technology. But at that time in Japan, only a few scientists were working on knockout mouse technology. That’s why I decided to move to the States, San Francisco

So I think failure is important in my career.

However, it was very natural that a failed surgeon with little experience in molecular biology had a hard time finding a position. A turning point came when I got a fax from Thomas Innerarity at the Gladstone Institute of Cardiovascular Diseases in San Francisco. After a short telephone conversation, Tom was brave enough to give me a postdoctoral position in his lab! Working at Gladstone was one of the best decisions I ever made in my life.

A book also pushed me to become a medical doctor. I was deeply inspired by Torao Tokuda, a physician who founded a hospital group in the 1970s that tried to revolutionize the Japanese medical care system.