What advice would you give your twenty-year-old self, and what should they ignore?
Recorded Richard Feynman said elsewhere, not written here
So I wish to you—I have no more time, so I have just one wish for you—the good luck to be somewhere where you are free to maintain the kind of integrity I have described, and where you do not feel forced by a need to maintain your position in the organization, or financial support, or so on, to lose your integrity. May you have that freedom. May I also give you one last bit of advice: Never say that you'll give a talk unless you know clearly what you're going to talk about and more or less what you're going to say.

Caltech commencement address, Pasadena, California, Caltech Engineering and Science (Caltech Library archive), 1 June 1974 source ↗

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Frederick W. Smith Founder and long-serving chairman of FedEx Corporation
The most important piece of advice that I could give them is to take advantage of the tremendous reservoir of knowledge that’s out there today. Spend some time learning how the world has evolved. There are a lot of good lessons in history, and other peoples’ experiences in the past, that could be exactly the solution to the problem you’re looking for.
Recorded Academy of Achievement interview, 23 May 1998 source ↗
Willem Kolff Physician and inventor; builder of the first practical artificial kidney
By the way, the guys with very high grades are not necessarily the people that are the most successful in later life. They may be the ones that can regurgitate gracefully, and they get very high grades. But if the guys that have to work for it and do not have such good grades can do something extra, and prove that they can perform, they may have a chance.
Recorded Academy of Achievement recorded interview, American Academy of Achievement source ↗
Nora Ephron Journalist, essayist, screenwriter and film director
My advice to everyone is: “Become a journalist.” ... if you have a chance to be a newspaper reporter for three or four years — before you do whatever you want to do — do it, because you will know so much.
Recorded Academy of Achievement interview, 21 June 2007 source ↗
Marvin Minsky Cognitive scientist; co-founder of the MIT Artificial Intelligence Laboratory
So any student who wants to get into psychology, right now the students are like lemmings. They say, “Well, it’s popular to study brain science, I’ll do that.” Or, “It’s popular to do neural networks; I see 30,000 people doing it, it must be good.” And my advice is if a lot of people are doing it, don’t waste your time.
Recorded Academy of Achievement interview, 4 May 2001 source ↗

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Question What do you need to believe in order to get through the day? Values & belief
I don’t believe I can really do without teaching.  The reason is, I have to have something so that when I don’t have any ideas and I’m not getting anywhere I can say to myself, “At least I’m living; at least I’m doing something; I’m making some contribution”—it’s just psychological.
Recorded Excerpt from “Surely You’re Joking, Mr. Feynman”, Engineering and Science / Caltech Magazine, 1985 source ↗
Question What is the most important lesson life has taught you? Time & hindsight
It is necessary, I believe, to accept this idea, not only for science, but also for other things; it is of great value to acknowledge ignorance.  It is a fact that when we make decisions in our life we don't necessarily know that we are making them correctly; we only think that we are doing the best we can – and that is what we should do.
Recorded Caltech YMCA Lunch Forum, Engineering and Science / Caltech Magazine, 2 May 1956 source ↗

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