You must find a way to get in the way, you must find a way to get into trouble — good trouble, necessary trouble.

I'd say be just like you. I once had someone tell me that I don't remind them of anyone that they ever met. And I took that as a huge compliment, which meant I was original. And so I would suggest to her that she speak her truth with her life, with her own sense of purpose and pursue her dreams.

So given a Time Turner, I would tell my 21-year-old self that personal happiness lies in knowing that life is not a check-list of acquisition or achievement. Your qualifications, your CV, are not your life, though you will meet many people of my age and older who confuse the two. Life is difficult, and complicated, and beyond anyone’s total control, and the humility to know that will enable you to survive its vicissitudes.

But whenever you do find something — maybe it’s not as passionate for you as dog mushing has been for me — but the fact that you have any interest, that is what you should go with.

I had lots of teachers encourage me. And I still know some of them, my high school teachers. But one of them encouraged me. She said, “Well, what do you want to do?” I said, “I want to be a doctor.” And she asked me where I wanted to go to school, and so I named all the Florida public universities which seemed within reach, financially. And she said, “Well, maybe you ought to apply to Duke, and maybe you’ll get a scholarship.” And I did both those things. I applied and got a scholarship. Her name is Wendy Tellone, and she’s still involved in public school teaching. I think she’s still in Florida.

I had lots of teachers encourage me. And I still know some of them, my high school teachers. But one of them encouraged me. She said, “Well, what do you want to do?” I said, “I want to be a doctor.” And she asked me where I wanted to go to school, and so I named all the Florida public universities which seemed within reach, financially. And she said, “Well, maybe you ought to apply to Duke, and maybe you’ll get a scholarship.” And I did both those things. I applied and got a scholarship.

And some of the things that we saw in the ’80s, really, they were failures, because patients died. But they allowed us to diagnose the systems’ problems and say, “This is where we need a community health worker system. This is where we need to make sure patients have food support while they’re getting these medicines,” et cetera. So those are examples of tragedies that certainly lead to — not just personal epiphanies — but collective epiphanies, where you say, “You know what? We can do this better if we have the system fixed.”