There are many times for three months in a row I wrote every day, but there are also many times for three months in a row I didn't write a word. What I found is I make an appointment with myself and I don't look at each day, I look at the calendar ahead.

In the first 33 years of my life which is up until I climbed Everest, I was a very restless and slightly unhappy sort of person. I really didn’t have a great deal of social life, but I’d become very interested in adventurous activities. Perhaps, I was, in some respects something of a loner. But after I got married, that certainly changed my life very considerably, indeed. I found that it was possible to mix having a family with continuing on with adventurous activities, but I think a great deal of that was having a suitable wife. My wife was very, long-suffering. She knew that there were certain things I wanted to do and she was happy that I should do them. She was prepared to put up with considerable periods of being alone with the kids. She, was marvelous, so it made it possible for me to do the things that I wanted to do as well.

It’s difficult. You really have to do it as best you can. Because your family is important too. You can’t be so totally absorbed that you are not involved in their activities as well. So, I tried to divorce the two as best I could.

It's hard - truthfully the main thing other than work is just making sure that I'm spending enough time with michelle and the girls. The big advantage I have is that I live above the store - so I have no commute! So we make sure that when I'm in DC I never miss dinner with them at 6:30 pm - even if I have to go back down to the Oval for work later in the evening. I do work out every morning as well, and try to get a basketball or golf game in on the weekends just to get out of the bubble.

people in power tend to take advantage of that power and this can be both men and women.

But you know that there are so many people that are equal to us or better that didn’t get the prize. You cannot go round the whole world and ask “are you better than me?”

I still don’t understand everything about the ribosome. I must say that the more lectures I give and the more questions that I get, the more thoughts they trigger. And also, we are now interested in the proto-ribosome, how life started. So we are trying to understand this and this really excites me, not just from the point of view of philosophy, we are trying to show it.

Oh ya, I doubted more than expected. I had doubts all the time. The way was extremely, extremely difficult. … At one point I had to describe what I am doing to a person who is a great intellectual but not a scientist, and I told him what we felt is that we are climbing mountains in order to reach the climax – and these mountains are like the Everest, the biggest most difficult to climb – only to find out that there is another mountain waiting behind it to be climbed afterwards. So every climbing was an achievement but there was a bigger problem behind it or above it. I had lots of minutes that I didn't expect, but I thought science in general and this science particularly is worth the effort – even if we would never get the ultimate result.

When I was a child and interested in discoveries, the first book that made an impression on me was called “Discoveries of the World” but it wasn’t about geography, it was about Marie Curie! [laughs] And then there is a beautiful Italian story – from the mountains in Italy to the Pyrenees, a kid goes to look for a flower with a golden heart inside for his ill mother. This made a big impression on me.  I also read lots of Isreali authors that you probably haven’t heard of.

Ultimately, my research was curiosity driven, which kept me active even in low periods.