What counsel would you give your twenty-year-old self — and what should they ignore?

Courage is more exhilarating than fear and in the long run it is easier. We do not have to become heroes overnight. Just a step at time, meeting each thing that comes up, seeing it is not as dreadful as it appeared, discovering we have the strength to stare it down.

Always remember that it's much easier to apologize than to get permission. In this world of computers, the best thing to do is to do it.

Study. Be honest. Don’t violate the laws and get in trouble. Get you a good spouse that will support you, because you never stop working and studying. The fact that you get the place just means you’ve started as far as the work and the pressure is concerned. That’s the only advice I’d know to give.

You have to be intelligent, and be able to cope with stress. It is a stressful life, both mentally and physically. Those are the qualities to succeed as a surgeon.

I would advise them to aim high. To set their sights at a pretty tough target and don’t be too worried if you’re not successful at first. Just keep persisting and keep improving your standards, getting better and better and ultimately, you’ve got a pretty fair chance at achieving your desired goal. ... But, I do think that virtually everybody that’s born has the ability to be very competent at doing something. I think that, in itself, is worthy of aiming towards, just to be competent at doing anything you particularly wish to do.

The advice I would give any young person is, first of all, to rid themselves of prejudice against other people and to be concerned about what they can do to help others. And of course, to get a good education, and take advantage of the opportunities that they have. In fact, there are more opportunities today than when I was young.

The sky has turned brighter. There is a glorious rainbow that beckons those with the spirit of adventure. And there are rich findings at the end of that rainbow. To the young and the not too old, I say, look at the horizon, find that rainbow, go ride it. Not all will be rich; quite a few will find a vein of gold; but all who pursue that rainbow will have a joyous and exhilarating ride and some profit.

Get on with it. But make sure you do want to do it. I think that’s the important thing, to be something that you would enjoy. If you only just go into science to get rich or to win gold medals, then I wouldn’t bother, but if you really want to enjoy yourself in the lab, then do it.

So any student who wants to get into psychology, right now the students are like lemmings. They say, “Well, it’s popular to study brain science, I’ll do that.” Or, “It’s popular to do neural networks; I see 30,000 people doing it, it must be good.” And my advice is if a lot of people are doing it, don’t waste your time.

Luckily, I got at a very early age the idea that the safest way to try and get what you want is to try and deserve what you want. It's such a simple idea. It's the golden rule so to speak. You want to deliver to the world what you would buy if you were on the other end. There is no ethos, in my opinion, that is better for any lawyer or any other person to have.

Study broadly. Don’t specialize too early. Read history. Sooner or later, you’re going to have to specialize, but within the limits that you have to take obligatory courses to get a degree, keep your general education as broad as you can, because you never know what doors are going to open to new opportunities — ten, 15, 20 years down the road — because of changes in science and technology.

I just say, “Follow your instincts.” Don’t feel you have to follow the paths of others, because you may not be temperamentally fitted for it. And so you’ll just harm yourself and your cause and others. But just follow your instinct, and don’t ever pretend to be what you’re not.

Write slowly and by hand only about subjects that interest you. […] Develop craftsmanship through years of wide reading.

I would hope that most of you will in fact strive for leadership in a principled manner with values, because that would be the foundation that this country needs to have if it is to take its place in the world. I would hope that each of you would lead by example and that each of you would live by the principles that you espouse.

So I urge my sisters, and my brothers, not to be afraid. Be not afraid to denounce injustice, though you may be outnumbered. Be not afraid to seek peace, even if your voice may be small. Be not afraid to demand peace.

Everything I did, and I think everything Martin Luther King did, was because we allowed our lives to be in tune with what we felt to be a divine purpose. And it didn’t matter whether we lived or died. It didn’t matter how much money we made, or what we accomplished.

You must find a way to get in the way, you must find a way to get into trouble — good trouble, necessary trouble.

Certainly, if you want to get into the field of biology these days, you should also study anthropology because so much work now is with communities. How do you help communities? How do you convince communities to protect their environment? — Especially if, let’s say, you have a tiger eating your cows. The natural gesture is to kill that tiger. Well, what are the alternatives? That’s the kind of thing one is now increasingly working with.

No. Go for it, as I did it. Go for all the mistakes. I made so many mistakes in doing my films. They all have a stutter or a limp or they are squint-eyed. Hardly anyone notices it, but I notice. Make your mistakes. Get arrested if you trespass. Yes. Do it. There’s nothing wrong with spending a night or two in jail. I’ve done that. Don’t be afraid of the grizzly bear behind you. Travel on foot. Read books.