How has a setback or failure set you up for later success?

It is not the critic who counts; not the man who points out how the strong man stumbles or where the doer of deeds could have done them better. The credit belongs to the man who is actually in the arena, whose face is marred by dust and sweat and blood; who strives valiantly; who errs, and comes short again and again, because there is no effort without error and shortcoming; but who does actually strive to do the deeds; who knows the great enthusiasms, the great devotions; who spends himself in a worthy cause; who at the best knows in the end the triumph of high achievement, and who at the worst, if he fails, at least fails while daring greatly, so that his place shall never be with those cold and timid souls who know neither victory nor defeat.

I would try to write my war story, whether it was interesting or not, and try to make something out of it. I describe that process a little in the beginning of Slaughterhouse Five; I saw it as starring John Wayne and Frank Sinatra. Finally, a girl called Mary O’Hare, the wife of a friend of mine who’d been there with me, said, “You were just children then. It’s not fair to pretend that you were men like Wayne and Sinatra, and it’s not fair to future generations, because you’re going to make war look good.” That was a very important clue to me.

You called it vision, I call it analyzing what my strengths were. It just so happened there was no market whatsoever for my strength, unless I was interested in becoming a show dancer, for which I tried, but I’m not tall enough. Also, when I auditioned for the Radio City Rockettes, they said, “We love your fouettés, but can’t you smile?” And things of that nature transpired between me and a commercial future. So, I managed to find a way of subsisting in the beginning by doing odd jobs, Kelly Girl temp work, selling perfume at Macy’s, and any and everything to be able to sustain studying and beginning a career with a group of dancers who were willing to devote five years, really, of their lives to me, working very seriously, with complete commitment, for not a penny.

As I was lazy and rarely did my homework, I finished high school with a rather mediocre exam. I almost did not pass in English language. Recently, my previous teachers allowed me to see their report on my high school performances, which included the following statements: Despite the fact that her talents are rather equally spread among many areas of knowledge, her performances are rather different depending on the distribution of her interests. Thus, with her strong display of self will she can be decidedly lazy in some topics over years, while in her areas of interests she performs to a degree far extending that required for normal school purposes.

I tried for a Ph.D. scholarship to work with Cedric Mims, but was told to apply again later because he already had a "scholar" and would take only one student at a time. … The following week a job in the Department of Experimental Pathology at the Moredun was advertized in Nature. We sailed for Britain in early 1967, on a very slow and cheap ship.

Oh, absolutely. I think most overachievers are driven, not so much by the pursuit of success, but by the fear of failure. Unless failure gets very close and very nearby that fear doesn’t reach profound levels, but it drives us. It drives me to work very hard.

And so I finally felt that I’d given up. ... And towards the morning, I started thinking, “Well, failure is actually what most people experience in boxing.” ... And I found a way to write about the whole sport by way of beginning with failure, with the image of failure.

I was a student at Yale and wrote a paper about the computerized society that was on the horizon. ... Then I sort of let that lie. I didn’t get a particularly good grade on it, as I recall.

I was writing poetry. But I found the theater such an exciting experience that one day I went home to try. I had one character say to the other guy, “Hey, man, what’s happening.” And the other guy said, “Nothing.” I sat there for twenty minutes and neither of my guys would talk. So 1 said to myself, “Well, that’s all right. After all, I’m a poet. I don’t have to be a playwright. To hell with writing plays. Let other people write plays.” I didn’t try to write a play for a number of years after that first experience.

Whenever you’re making a movie, especially when you’re writing, you always have self-doubts. I did the first location shooting in Tunisia.

about 95% of the experiments we do are total failures, and that’s because we’re out there on the leading edge of what’s possible, and most of the time it isn’t quite possible.

The world would say it was failure. But the difference was so small between us. They played great, but they lost.

I didn't see it then, but it turned out that getting fired from Apple was the best thing that could have ever happened to me. The heaviness of being successful was replaced by the lightness of being a beginner again, less sure about everything. It freed me to enter one of the most creative periods of my life.

And some of the things that we saw in the ’80s, really, they were failures, because patients died. But they allowed us to diagnose the systems’ problems and say, “This is where we need a community health worker system. This is where we need to make sure patients have food support while they’re getting these medicines,” et cetera. So those are examples of tragedies that certainly lead to — not just personal epiphanies — but collective epiphanies, where you say, “You know what? We can do this better if we have the system fixed.”

Well, I'll be honest with you. I was a theoretical physicist but my Ph.D. work was on a problem that was not particularly interesting to me at the time. And I used to subscribe to Scientific American and I found that there were all these wonderful discoveries happening in biology and I also knew that a number of physicists had gone into biology and been successful. So, I decided to switch.

Working at the hospital, I found that my surgical skills were not as good as I expected. One time it took me two hours to do a surgical operation which could have been completed in 30 minutes by other surgeons. My supervisors were very tough on new residents like me, and I lost confidence in my ability.

I don’t know. That’s a terrible answer I realise, and everyone wants a nice straight forward answer. I think everyone, all scientists, have these kind of wacky ideas along the way, and some of them work and some of them don’t work. And this was one that, you know, came and was successful and went forward, and again it sounds obvious to say we were lucky – but we were lucky, you know, there’s way more ideas fail than ever succeed, and this was one that, you know, we were very excited about at the beginning, we thought it had a very low probability of success, but it took off, and it took off like gangbusters. That was wonderful to see.